Article
Gene-gene and gene-environment interactions on risk of male infertility: Focus on the metabolites.
Environment international - 1 May 2016
Hu Weiyue, Chen Minjian, Wu Wei, Lu Jing, Zhao Dan, Pan Feng, Lu Chuncheng, Xia Yankai, Hu Lingqing, Chen Daozhen, Sha Jiahao, Wang Xinru
Abstract excerpt
Infertility affects about 17% couples, and males contribute to half of the cases. Compared with independent effects of genetic and environmental factors, interactions between them help in the understanding of the susceptibility to male infertility. Thus, we genotyped 25 polymorphisms, measured 16 urinary chemical concentrations and explored interactions between gene-gene and gene-environment in 1039 Han Chinese...
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