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Article

A Homozygous RAB3GAP1:c.743delC Mutation in Rottweilers with Neuronal Vacuolation and Spinocerebellar Degeneration.

Journal of veterinary internal medicine - 1 May 2016

Mhlanga-Mutangadura T, Johnson G S, Ashwini A, Shelton G D, Wennogle S A, Johnson G C, Kuroki K, O'Brien D P

Abstract excerpt

BACKGROUND: A variety of presumed hereditary, neurologic diseases have been reported in young Rottweilers. Overlapping ages of onset and clinical signs have made antemortem diagnosis difficult. One of these diseases, neuronal vacuolation and spinocerebellar degeneration (NVSD) shares clinical and histological features with polyneuropathy with ocular abnormalities and neuronal vacuolation (POANV), a recently...

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PMID: 26968732
DOI: 10.1111/jvim.13921
PMCID: PMC4913561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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