Article
Increased detection in Australia and Singapore of a novel influenza A(H1N1)2009 variant with reduced oseltamivir and zanamivir sensitivity due to a S247N neuraminidase mutation.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 9 Jun 2011
Hurt A C, Lee R T, Leang S K, Cui L, Deng Y M, Phuah S P, Caldwell N, Freeman K, Komadina N, Smith D, Speers D, Kelso A, Lin R T, Maurer-Stroh S, Barr I G
Abstract excerpt
A novel influenza A(H1N1)2009 variant with mildly reduced oseltamivir and zanamivir sensitivity has been detected in more than 10% of community specimens in Singapore and more than 30% of samples from northern Australia during the early months of 2011. The variant, which has also been detected in other regions of the Asia-Pacific, contains a S247N neuraminidase mutation. When combined with the H275Y mutation, as...
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