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Article

HapX Mediates Iron Homeostasis in the Pathogenic Dermatophyte Arthroderma benhamiae but Is Dispensable for Virulence.

PloS one - 1 Jan 2016

Kröber Antje, Scherlach Kirstin, Hortschansky Peter, Shelest Ekaterina, Staib Peter, Kniemeyer Olaf, Brakhage Axel A

Abstract excerpt

For many pathogenic fungi, siderophore-mediated iron acquisition is essential for virulence. The process of siderophore production and further mechanisms to adapt to iron limitation are strictly controlled in fungi to maintain iron homeostasis. Here we demonstrate that the human pathogenic dermatophyte Arthroderma benhamiae produces the hydroxamate siderophores ferricrocin and ferrichrome C. Additionally, we show...

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Identifiers

PMID: 26960149
DOI: 10.1371/journal.pone.0150701
PMCID: PMC4784894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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