Article
Highly efficient de novo mutant identification in a Sorghum bicolor TILLING population using the ComSeq approach.
The Plant journal : for cell and molecular biology - 1 May 2016
Nida Habte, Blum Shula, Zielinski Dina, Srivastava Dhruv A, Elbaum Rivka, Xin Zhanguo, Erlich Yaniv, Fridman Eyal, Shental Noam
Abstract excerpt
Screening large populations for carriers of known or de novo rare single nucleotide polymorphisms (SNPs) is required both in Targeting induced local lesions in genomes (TILLING) experiments in plants and in screening of human populations. We previously suggested an approach that combines the mathematical field of compressed sensing with next-generation sequencing to allow such large-scale screening. Based on...
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