Article
Sustained transmission of high-level azithromycin-resistant Neisseria gonorrhoeae in England: an observational study.
The Lancet. Infectious diseases - 1 May 2018
Fifer Helen, Cole Michelle, Hughes Gwenda, Padfield Simon, Smolarchuk Christa, Woodford Neil, Wensley Adrian, Mustafa Nazim, Schaefer Ulf, Myers Richard, Templeton Kate, Shepherd Jill, Underwood Anthony
Abstract excerpt
BACKGROUND: Between Nov 3, 2014, and Feb 24, 2017, 70 cases of high-level azithromycin-resistant (HL-AziR; minimum inhibitory concentration [MIC] ≥256 mg/L) Neisseria gonorrhoeae were reported from across England. Whole-genome sequencing was done to investigate this outbreak to determine whether the ongoing outbreak represented clonal spread of an HL-AziR N gonorrhoeae strain identified in Leeds. We also wanted...
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