Article
The significance of naturally occurring neuraminidase quasispecies of H5N1 avian influenza virus on resistance to oseltamivir: a point of concern.
The Journal of general virology - 1 Jun 2016
Schaduangrat Nalini, Phanich Jiraphorn, Rungrotmongkol Thanyada, Lerdsamran Hatairat, Puthavathana Pilaipan, Ubol Sukathida
Abstract excerpt
Viral adaptability and survival arise due to the presence of quasispecies populations that are able to escape the immune response or produce drug-resistant variants. However, the presence of H5N1 virus with natural mutations acquired without any drug selection pressure poses a great threat. Cloacal samples collected from the 2004-2005 epidemics in Thailand from Asian open-billed storks revealed one major and...
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