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Article

Study of drug resistance of chicken influenza A virus (H5N1) from homology-modeled 3D structures of neuraminidases.

Biochemical and biophysical research communications - 16 Mar 2007

Wang Shu-Qing, Du Qi-Shi, Chou Kou-Chen

Abstract excerpt

The spread of highly pathogenic H5N1 influenza virus in many Asian and European countries as well as its drug-resistance have raised serious worldwide concerns. In this paper, the structure-activity relationship between NA (neuraminidase) and its three inhibitors (DANA, zanamivir, and oseltamivir) was investigated. A homology model of H5N1-NA (BAE46950), which is the first reported oseltamivir-resistance virus...

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Identifiers

PMID: 17266937
DOI: 10.1016/j.bbrc.2006.12.235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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