Cyclooxygenase 2 (rs2745557) Polymorphism and the Susceptibility to Benign Prostate Hyperplasia and Prostate Cancer in Egyptians.

doi:10.1007/s10528-016-9722-4

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Cyclooxygenase 2 (rs2745557) Polymorphism and the Susceptibility to Benign Prostate Hyperplasia and Prostate Cancer in Egyptians.

Biochemical genetics - 1 Jun 2016

Fawzy Mohamed S, Elfayoumi Abdel-Rahman, Mohamed Randa H, Fatah Ihab R Abdel, Saadawy Sara F

Abstract excerpt

Cyclooxygenase-2 (COX-2), an inducible isoform of cyclooxygenase, has been reported to be correlated with tumorigenesis, tumor progression, and metastasis. We aimed to evaluate the association between COX-2 (rs2745557) polymorphism and prostate cancer (PCa), benign prostate hyperplasia (BPH) risk. We also assessed the influence of other risk factors such as obesity, smoking, diabetes in modulating the risk of PCa...

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PMID: 26920155
DOI: 10.1007/s10528-016-9722-4

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