Article
Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.
Cell cycle (Georgetown, Tex.) - 1 Jan 2016
Borgal Lori, Rinschen Markus M, Dafinger Claudia, Liebrecht Valérie I, Abken Hinrich, Benzing Thomas, Schermer Bernhard
Abstract excerpt
The PHD zinc finger protein Jade-1S is a component of the HBO1 histone acetyltransferase complex and binds chromatin in a cell cycle-dependent manner. Jade-1S also acts as an E3 ubiquitin ligase for the canonical Wnt effector protein β-catenin and is influenced by CK1α-mediated phosphorylation. To further elucidate the functional impact of this phosphorylation, we used a stable, low-level expression system to...
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