Article
A Novel Analog Reasoning Paradigm: New Insights in Intellectually Disabled Patients.
PloS one - 1 Jan 2016
Curie Aurore, Brun Amandine, Cheylus Anne, Reboul Anne, Nazir Tatjana, Bussy Gérald, Delange Karine, Paulignan Yves, Mercier Sandra, David Albert, Marignier Stéphanie, Merle Lydie, de Fréminville Bénédicte, Prieur Fabienne, Till Michel, Mortemousque Isabelle, Toutain Annick, Bieth Eric, Touraine Renaud, Sanlaville Damien, Chelly Jamel, Kong Jian, Ott Daniel, Kassai Behrouz, Hadjikhani Nouchine, Gollub Randy L, des Portes Vincent
Abstract excerpt
BACKGROUND: Intellectual Disability (ID) is characterized by deficits in intellectual functions such as reasoning, problem-solving, planning, abstract thinking, judgment, and learning. As new avenues are emerging for treatment of genetically determined ID (such as Down's syndrome or Fragile X syndrome), it is necessary to identify objective reliable and sensitive outcome measures for use in clinical trials....
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