Article
Assessing cognitive improvement in people with Down syndrome: important considerations for drug-efficacy trials.
Handbook of experimental pharmacology - 1 Jan 2015
Fernandez Fabian, Reeves Roger H
Abstract excerpt
Experimental research over just the past decade has raised the possibility that learning deficits connected to Down syndrome (DS) might be effectively managed by medication. In the current chapter, we touch on some of the work that paved the way for these advances and discuss the challenges associated with translating them. In particular, we highlight sources of phenotypic variability in the DS population that...
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