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Article

Predictability of Phenotype in Relation to Common β-Lactam Resistance Mechanisms in Escherichia coli and Klebsiella pneumoniae.

Journal of clinical microbiology - 1 May 2016

Agyekum Alex, Fajardo-Lubián Alicia, Ai Xiaoman, Ginn Andrew N, Zong Zhiyong, Guo Xuejun, Turnidge John, Partridge Sally R, Iredell Jonathan R

Abstract excerpt

The minimal concentration of antibiotic required to inhibit the growth of different isolates of a given species with no acquired resistance mechanisms has a normal distribution. We have previously shown that the presence or absence of transmissible antibiotic resistance genes has excellent predictive power for phenotype. In this study, we analyzed the distribution of six β-lactam antibiotic susceptibility...

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Identifiers

PMID: 26912748
DOI: 10.1128/JCM.02153-15
PMCID: PMC4844708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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