Article
Mucosa-Associated Invariant T Cells Are Systemically Depleted in Simian Immunodeficiency Virus-Infected Rhesus Macaques.
Journal of virology - 1 May 2016
Vinton Carol, Wu Fan, Rossjohn Jamie, Matsuda Kenta, McCluskey James, Hirsch Vanessa, Price David A, Brenchley Jason M
Abstract excerpt
UNLABELLED: Mucosa-associated invariant T (MAIT) cells contribute to host immune protection against a wide range of potential pathogens via the recognition of bacterial metabolites presented by the major histocompatibility complex class I-related molecule MR1. Although bacterial products translocate systemically in human immunodeficiency virus (HIV)-infected individuals and simian immunodeficiency virus...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
