Probiotic <i>Lactobacillus casei</i> strain Shirota relieves stress‐associated symptoms by modulating the gut–brain interaction in human and animal models

Abstract excerpt

BACKGROUND: This study aimed to examine the effects of Lactobacillus casei strain Shirota (LcS) on gut-brain interactions under stressful conditions. METHODS: Three double-blind, placebo-controlled trials were conducted to examine the effects of LcS on psychological and physiological stress responses in healthy medical students under academic examination stress. Subjects received LcS-fermented milk or placebo...

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