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Article

GATA4 regulates Fgf16 to promote heart repair after injury.

Development (Cambridge, England) - 15 Mar 2016

Yu Wei, Huang Xiuzhen, Tian Xueying, Zhang Hui, He Lingjuan, Wang Yue, Nie Yu, Hu Shengshou, Lin Zhiqiang, Zhou Bin, Pu William, Lui Kathy O, Zhou Bin

Abstract excerpt

Although the mammalian heart can regenerate during the neonatal stage, this endogenous regenerative capacity is lost with age. Importantly, replication of cardiomyocytes has been found to be the key mechanism responsible for neonatal cardiac regeneration. Unraveling the transcriptional regulatory network for inducing cardiomyocyte replication will, therefore, be crucial for the development of novel therapies to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26893347
DOI: 10.1242/dev.130971

Genes

GATA4
FGF16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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