Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria

Abstract excerpt

INTRODUCTION: Extended spectrum β-lactamases (ESBL) and AmpC β-lactamases are increasing causes of resistance in many Gram-negative pathogens of common infections. This has led to a growing utilization of broad spectrum antibiotics, most predominately the carbapenem agents. As the prevalence of ESBL and AmpC-producing isolates and carbapenem resistance has increased, interest in effective alternatives for the...

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