Article
Clinical impact of mutation fraction in epidermal growth factor receptor mutation positive NSCLC patients.
British journal of cancer - 15 Mar 2016
Martin Petra, Shiau Carolyn J, Pasic Maria, Tsao Ming, Kamel-Reid Suzanne, Lin Stephanie, Tudor Roxana, Cheng Susanna, Higgins Brian, Burkes Ronald, Ng Matilda, Arif Saroosh, Ellis Peter M, Hubay Stacy, Kuruvilla Sara, Laurie Scott A, Li Jing, Hwang David, Lau Anthea, Shepherd Frances A, Le Lisa W, Leighl Natasha B
Abstract excerpt
BACKGROUND: We examined clinical outcomes in a population-based cohort of EGFR mutant advanced NSCLC patients, exploring the potential role of factors including tumour EGFR mutation fraction and cellularity in predicting outcomes. METHODS: A cohort of patients with EGFR mutant advanced NSCLC was identified (N =2 93); clinical outcomes, pathologic and treatment details were collected. Tumour response was...
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