Article
Genetic Homozygosity and Phenotypic Variability in Craniosynostotic Rabbits.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2017
Gilbert James R, Cray James J, Kreithen Amy, Marazita Mary L, Cooper Gregory M, Losee Joseph E, Siegel Michael I, Mooney Mark P
Abstract excerpt
BACKGROUND: Craniosynostosis ranges in severity from single suture involvement with prenatal onset to multiple suture involvement with postnatal onset. The present study was designed to test the hypothesis that increasing homozygosity may be responsible for more severe phenotypic expression by examining the relationship between inbreeding and phenotypic expression in synostotic rabbits. METHODS: Data were...
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