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Article

Sensitive windows of skeletal development in rabbits determined by hydroxyurea exposure at different times throughout gestation.

Birth defects research. Part B, Developmental and reproductive toxicology - 1 Jun 2012

Campion Sarah N, Davenport Scott J, Nowland William S, Cappon Gregg D, Bowman Christopher J, Hurtt Mark E

Abstract excerpt

The critical periods of axial skeletal development in rats and mice have been well characterized, however the timing of skeletal development in rabbits is not as well known. It is important to have a more precise understanding of this timing of axial skeletal development in rabbits due to the common use of this species in standard nonclinical studies to assess embryo-fetal developmental toxicity. Hydroxyurea, a...

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PMID: 22495808
DOI: 10.1002/bdrb.21013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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