FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome.

doi:10.1038/srep21195

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Article

FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome.

Scientific reports - 16 Feb 2016

Tian Ye, Zhang Wei, Zhao Shigang, Sun Yinhua, Bian Yuehong, Chen Tailai, Du Yanzhi, Zhang Jiangtao, Wang Zhao, Huang Tao, Peng Yingqian, Yang Ping, Zhao Han, Chen Zi-Jiang

Abstract excerpt

Dyslipidemia is common in polycystic ovary syndrome (PCOS). This study was aimed to investigate whether fatty acid desaturase genes (FADS), a dyslipidemia-related gene cluster, are associated with PCOS. We scanned variations of FADS genes using our previous data of genome-wide association study (GWAS) for PCOS and selected rs174570 for further study. The case-control study was conducted in an independent cohort...

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Identifiers

PMID: 26879377
DOI: 10.1038/srep21195
PMCID: PMC4754766

Genes

FADS2
FADS1

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