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Article

OncoBinder facilitates interpretation of proteomic interaction data by capturing coactivation pairs in cancer.

Oncotarget - 5 Apr 2016

Van Coillie Samya, Liang Lunxi, Zhang Yao, Wang Huanbin, Fang Jing-Yuan, Xu Jie

Abstract excerpt

High-throughput methods such as co-immunoprecipitationmass spectrometry (coIP-MS) and yeast 2 hybridization (Y2H) have suggested a broad range of unannotated protein-protein interactions (PPIs), and interpretation of these PPIs remains a challenging task. The advancements in cancer genomic researches allow for the inference of "coactivation pairs" in cancer, which may facilitate the identification of PPIs...

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Identifiers

PMID: 26872056
DOI: 10.18632/oncotarget.7305
PMCID: PMC4951236

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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