Article
The status of epidermal growth factor receptor in borderline ovarian tumours.
Oncotarget - 1 Mar 2016
Showeil Rania, Romano Claudia, Valganon Mikel, Lambros Maryou, Trivedi Pritesh, Van Noorden Susan, Sriraksa Ruethairat, El-Kaffash Dalal, El-Etreby Nour, Natrajan Rachael, Foroni Letizia, Osborne Richard, El-Bahrawy Mona
Abstract excerpt
The majority of borderline ovarian tumours (BOTs) behave in a benign fashion, but some may show aggressive behavior. The reason behind this has not been elucidated. The epidermal growth factor receptor (EGFR) is known to contribute to cell survival signals as well as metastatic potential of some tumours. EGFR expression and gene status have not been thoroughly investigated in BOTs as it has in ovarian carcinomas....
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