Article
Reduced Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI).
EBioMedicine - 1 Jan 2016
Georgopoulos Apostolos P, James Lisa M, Mahan Margaret Y, Joseph Jasmine, Georgopoulos Angeliki, Engdahl Brian E
Abstract excerpt
BACKGROUND: Gulf War Illness (GWI) is a disease of unknown etiology with symptoms suggesting the involvement of an immune process. Here we tested the hypothesis that Human Leukocyte Antigen (HLA) composition might differ between veterans with and without GWI. METHODS: We identified 144 unique alleles of Class I and II HLA genes in 82 veterans (66 with and 16 without GWI). We tested the hypothesis that a subset of...
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