Article
rs6295 [C]-Allele Protects Against Depressive Mood in Elderly Endurance Athletes.
Journal of sport & exercise psychology - 1 Dec 2015
Haslacher Helmuth, Michlmayr Matthias, Batmyagmar Delgerdalai, Perkmann Thomas, Ponocny-Seliger Elisabeth, Scheichenberger Vanessa, Scherzer Thomas M, Nistler Sonja, Pilger Alexander, Dal-Bianco Peter, Lehrner Johann, Pezawas Lukas, Wagner Oswald F, Winker Robert
Abstract excerpt
A single nucleotide variant within the promoter of the 5-hydroxytryptamine1A (5HT1A) receptor, rs6295, is part of a binding site for the transcription factor. We aimed to ascertain whether the rs6295 mediates the effect of exercise on depressive mood in elderly endurance athletes. We prospectively enrolled 55 elderly athletes (marathon runners/bicyclists) and 58 controls. In a controlled, univariate model, an...
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