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Article

A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity.

Psychiatry research - 1 Mar 2017

Taylor Marcus K, Beckerley Shiloh E, Henniger Nicole E, Hernández Lisa M, Larson Gerald E, Granger Douglas A

Abstract excerpt

We evaluated associations of five candidate polymorphisms (Bcl1 [rs41423247], -2C/G [rs2070951], COMT [rs737865], Val66Met [rs6265], and 5HTTLPR [biallelic and triallelic [5HTTLPR/rs25531]) with probable MDD and suicidal ideation (SI), the effects of physical activity on these endpoints, and whether physical activity attenuates genetic risk in military members (N=736). C carriers who were also less physically...

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Source

Identifiers

PMID: 28142104
DOI: 10.1016/j.psychres.2017.01.002

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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