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Article

Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity.

BMC systems biology - 11 Feb 2016

Pavel Ana B, Sonkin Dmitriy, Reddy Anupama

Abstract excerpt

BACKGROUND: High throughput technologies have been used to profile genes in multiple different dimensions, such as genetic variation, copy number, gene and protein expression, epigenetics, metabolomics. Computational analyses often treat these different data types as independent, leading to an explosion in the number of features making studies under-powered and more importantly do not provide a comprehensive view...

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Identifiers

PMID: 26864072
DOI: 10.1186/s12918-016-0260-9
PMCID: PMC4750289

Genes

BRAF
EGFR
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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