Article
Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.
PloS one - 1 Jan 2016
Ho Jennifer E, Larson Martin G, Ghorbani Anahita, Cheng Susan, Chen Ming-Huei, Keyes Michelle, Rhee Eugene P, Clish Clary B, Vasan Ramachandran S, Gerszten Robert E, Wang Thomas J
Abstract excerpt
BACKGROUND: Although obesity and cardiometabolic traits commonly overlap, underlying pathways remain incompletely defined. The association of metabolite profiles across multiple cardiometabolic traits may lend insights into the interaction of obesity and metabolic health. We sought to investigate metabolic signatures of obesity and related cardiometabolic traits in the community using broad-based metabolomic...
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