Article
Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life events.
Biological psychiatry - 1 Sept 2014
Loth Eva, Poline Jean-Baptiste, Thyreau Benjamin, Jia Tianye, Tao Chenyang, Lourdusamy Anbarasu, Stacey David, Cattrell Anna, Desrivières Sylvane, Ruggeri Barbara, Fritsch Virgile, Banaschewski Tobias, Barker Gareth J, Bokde Arun L W, Büchel Christian, Carvalho Fabiana M, Conrod Patricia J, Fauth-Buehler Mira, Flor Herta, Gallinat Jürgen, Garavan Hugh, Heinz Andreas, Bruehl Ruediger, Lawrence Claire, Mann Karl, Martinot Jean-Luc, Nees Frauke, Paus Tomáš, Pausova Zdenka, Poustka Luise, Rietschel Marcella, Smolka Michael, Struve Maren, Feng Jianfeng, Schumann Gunter
Abstract excerpt
BACKGROUND: Common variants in the oxytocin receptor gene (OXTR) have been shown to influence social and affective behavior and to moderate the effect of adverse experiences on risk for social-affective problems. However, the intermediate neurobiological mechanisms are not fully understood. Although human functional neuroimaging studies have reported that oxytocin effects on social behavior and emotional states...
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