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Article

Sequence variant analysis of RNA sequences in severe equine asthma

11 Oct 2018

Abstract excerpt

Background Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. This study aimed to determine the utility of RNA-Seq to call gene sequence variants, and to identify sequence variants of potential relevance to the pathogenesis of asthma. Methods RNA-Seq data were generated from endobronchial biopsies collected from six asthmatic and seven...

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PMID: 30324028
DOI: 10.7717/peerj.5759

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