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Article

A new perspective on the genetics of keratoconus: why have we not been more successful?

Ophthalmic genetics - 1 Apr 2018

Valgaeren Hanne, Koppen Carina, Van Camp Guy

Abstract excerpt

Twin studies and family studies suggest an important genetic basis for keratoconus (KC). Involvement and association of several genes with the disease has been reported. Additionally, genes associated with central corneal thickness (CCT) and corneal curvature (CC) via genome-wide association studies (GWAS), also potentially underlie KC. Although a long list of genes has been reported for KC, the evidence for a...

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Source

Identifiers

PMID: 29111844
DOI: 10.1080/13816810.2017.1393831

Genes

MAF
SOD1
VSX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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