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Article

Two waves of transcriptomic changes in periovulatory human granulosa cells

24 Feb 2020

Abstract excerpt

STUDY QUESTION: How does the human granulosa cell (GC) transcriptome change during ovulation? SUMMARY ANSWER: Two transcriptional peaks were observed at 12 h and at 36 h after induction of ovulation, both dominated by genes and pathways known from the inflammatory system. WHAT IS KNOWN ALREADY: The crosstalk between GCs and the oocyte, which is essential for ovulation and oocyte maturation, can be assessed...

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PMID: 32378719
DOI: 10.1093/humrep/deaa043

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