Article
DNA repair gene ERCC1 polymorphisms may contribute to the risk of glioma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014
Yuan Guanqian, Gao Dandan, Ding Shaofeng, Tan Jun
Abstract excerpt
Polymorphisms in excision repair cross-complementing rodent repair deficiency complementation group 1 (ERCC1) gene have been shown to affect individual susceptibility to glioma, though studies have yielded conflicting results. This meta-analysis aims to derive a more precise estimation of the association between ERCC1 C8092A and C118T polymorphisms and glioma risk. A literature search of PubMed, Embase, Web of...
Topics
- Brain Neoplasms
- DNA-Binding Proteins
- Endonucleases
- Genetic Predisposition to Disease
- Glioma
- Humans
- Polymorphism, Genetic
- Publication Bias
- Risk
