Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential role of Wnt5a-Ror1/Ror2 signaling in metanephric mesenchyme and ureteric bud formation.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Apr 2016

Qi Xiaoyuan, Okinaka Yuka, Nishita Michiru, Minami Yasuhiro

Abstract excerpt

Spatiotemporally regulated interaction between the metanephric mesenchyme (MM) and Wolffian duct (WD) is essential for the induction of a single ureteric bud (UB). The MM then interacts with the tip of the UB to induce outgrowth and branching of the UB, which in turn promotes growth of the adjacent MM. The Ror family receptor tyrosine kinases, Ror1 and Ror2, have been shown to act as receptors for Wnt5a to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryo, Mammalian
Share to Kidney
Share to Mesoderm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Receptor Tyrosine Kinase-like Orphan Receptors

Share to Signal Transduction

Share to Ureter

Source

Identifiers

PMID: 26840931
DOI: 10.1111/gtc.12342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential role of Wnt5a-Ror1/Ror2 signaling in metanephric mesenchyme and ureteric bud formation.PMID 26840931Read ↗

Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extensionSemantic proximity Read ↗

Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded.Semantic proximity Read ↗

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway.Semantic proximity Read ↗

Role of noncanonical Wnt ligands and Ror‐family receptor tyrosine kinases in the development, regeneration, and diseases of the musculoskeletal systemSemantic proximity Read ↗

Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development.Semantic proximity Read ↗

Ureteric Morphogenesis Requires Fgfr1 and Fgfr2/Frs2α Signaling in the Metanephric MesenchymeSemantic proximity Read ↗

Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development.Semantic proximity Read ↗

Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B.Semantic proximity Read ↗

Lrp4 Regulates Initiation of Ureteric Budding and Is Crucial for Kidney Formation – A Mouse Model for Cenani-Lenz SyndromeSemantic proximity Read ↗

The Receptor Tyrosine Kinase Ror2 Associates with the Melanoma-associated Antigen (MAGE) Family Protein Dlxin-1 and Regulates Its Intracellular DistributionSemantic proximity Read ↗

osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2Semantic proximity Read ↗

Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.