Article
The generation of human innate lymphoid cells is influenced by the source of hematopoietic stem cells and by the use of G-CSF.
European journal of immunology - 1 May 2016
Moretta Francesca, Petronelli Francesca, Lucarelli Barbarella, Pitisci Angela, Bertaina Alice, Locatelli Franco, Mingari Maria Cristina, Moretta Lorenzo, Montaldo Elisa
Abstract excerpt
NK cells play a central role in the haploidentical HSC transplantation (HSCT) to cure high-risk leukemias. Other innate lymphoid cells (ILCs) have been proposed to exert a protective role in graft-versus-host disease and could also contribute to anti-microbial defence and to lymphoid tissue remodeling. Thus, we investigated the ILC differentiation potential of HSCs isolated from BM, mobilized peripheral blood...
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