Article
The significant role of a functional polymorphism in the NF-κB1 gene in breast cancer: evidence from an Iranian cohort.
Future oncology (London, England) - 1 Dec 2021
Alidoust Maryam, Shamshiri Asma Khorshid, Tajbakhsh Amir, Gheibihayat Seyed Mohammad, Mazloom Seyed Mostafa, Alizadeh Farzaneh, Pasdar Alireza
Abstract excerpt
Aims: Breast cancer (BC) is one of the most common cancers among women. The influence of genetic variations on BC risk has been thus far assessed via genome-wide association studies. NF-κB has been recognized as a major player in BC progression. In this study, the association between rs28362491 and BC was evaluated in a population from northeastern Iran. Materials & methods: This study was conducted on 476...
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