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Immunoglobulin G Expression in Human Sperm and Possible Functional Significance

1 Feb 2016

Abstract excerpt

Immunoglobulin G (IgG), the major molecule of the immune system, which was traditionally thought to be produced by differentiated B-lymphocytes, had recently been found in non-immune cells including spermatozoa of rabbit testis. To study if human sperms could produce IgG that might play a role in fertilization, we employed immunofluorescent staining, Western blot, in situ hybridization, RT-PCR (reverse...

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PMID: 26833114
DOI: 10.1038/srep20166

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