Article
Association of goat (Capra hircus) CD4 gene exon 6 polymorphisms with ability of sperm internalizing exogenous DNA.
Molecular biology reports - 1 Mar 2011
Wang Lingbin, Fan Jingsheng, Yu Mingju, Zheng Shuangyan, Zhao Yongju
Abstract excerpt
As one of the transport systems on the sperm plasma membrane, CD4 molecule plays a distinct role in the process of sperm/DNA interaction. This makes it possible to explain the mechanism of sperm-mediated gene transfer (SMGT), which at present is still a mystery in this area. In this study, seminal samples of 60 individuals from seven breed bucks were collected to detect the ability of sperm in internalizing...
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