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Article

DNA Repair Gene (XRCC1) Polymorphism (Arg399Gln) Associated with Schizophrenia in South Indian Population: A Genotypic and Molecular Dynamics Study.

PloS one - 1 Jan 2016

Sujitha S P, Kumar D Thirumal, Doss C George Priya, Aavula K, Ramesh R, Lakshmanan S, Gunasekaran S, Anilkumar G

Abstract excerpt

This paper depicts the first report from an Indian population on the association between the variant Arg399Gln of XRCC1 locus in the DNA repair system and schizophrenia, the debilitating disease that affects 1% of the world population. Genotypic analysis of a total of 523 subjects (260 patients and 263 controls) revealed an overwhelming presence of Gln399Gln in the case subjects against the controls (P < 0.0068),...

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Source

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Identifiers

PMID: 26824244
DOI: 10.1371/journal.pone.0147348
PMCID: PMC4732819

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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