Article
Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer.
Scientific reports - 29 Jan 2016
Sheng Jin, Fang Wenfeng, Yu Juan, Chen Nan, Zhan Jianhua, Ma Yuxiang, Yang Yunpeng, Huang Yan, Yanhuang, Zhao Hongyun, Zhang Li
Abstract excerpt
The effects of treatments to programmed death ligand-1 (PD-L1) expression is unknown. The aim of this study was to investigate the impact of neoadjuvant chemotherapy (NACT) on PD-L1 expression in non-small cell lung cancer (NSCLC) patients. PD-L1 expression was detected by immunohistochemistry (IHC) method in 32 paired tumor specimens pre and post-NACT. The positivity of PD-L1 on tumor cells (TCs) changed from...
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