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Article

PD-1/PD-L1 pathway in non-small-cell lung cancer and its relation with EGFR mutation.

Journal of translational medicine - 16 Jan 2015

Ji Mei, Liu Yan, Li Qing, Li Xiao-Dong, Zhao Wei-Qing, Zhang Hanze, Zhang Xiaofei, Jiang Jing-Ting, Wu Chang-Ping

Abstract excerpt

Immunotherapy has become a crucial modality for non-small-cell lung cancer treatment. Recently, two immune checkpoints, PD-1 and PD-L1, have emerged as important targets for immunotherapy. Their antitumor efficacy has been confirmed by in vitro and in vivo studies. But the correlation between PD-1/PD-L1 expression and EGFR expression was controversial and needs more evidences to support the combination of...

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Share to B7-H1 Antigen
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25592115
DOI: 10.1186/s12967-014-0373-0
PMCID: PMC4302082

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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PD-1/PD-L1 pathway in non-small-cell lung cancer and its relation with EGFR mutation.PMID 25592115Read ↗

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