Article
Molecular genetics and targeted therapeutics in biliary tract carcinoma.
World journal of gastroenterology - 28 Jan 2016
Marks Eric I, Yee Nelson S
Abstract excerpt
The primary malignancies of the biliary tract, cholangiocarcinoma and gallbladder cancer, often present at an advanced stage and are marginally sensitive to radiation and chemotherapy. Accumulating evidence indicates that molecularly targeted agents may provide new hope for improving treatment response in biliary tract carcinoma (BTC). In this article, we provide a critical review of the pathogenesis and genetic...
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