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Article

Lead exposure increases blood pressure by increasing angiotensinogen expression.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering - 1 Jan 2016

Jiao Jiandong, Wang Miaomiao, Wang Yiqing, Sun Na, Li Chunping

Abstract excerpt

Lead exposure can induce increased blood pressure. Several mechanisms have been proposed to explain lead-induced hypertension. Changes in angiotensinogen (AGT) expression levels or gene variants may also influence blood pressure. In this study, we hypothesized that AGT expression levels or gene variants contribute to lead-induced hypertension. A preliminary HEK293 cell model experiment was performed to analyze...

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Source

Identifiers

PMID: 26818744
DOI: 10.1080/10934529.2015.1120537

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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