Article
Klebsiella pneumoniae Is Able to Trigger Epithelial-Mesenchymal Transition Process in Cultured Airway Epithelial Cells.
PloS one - 1 Jan 2016
Leone Laura, Mazzetta Francesca, Martinelli Daniela, Valente Sabatino, Alimandi Maurizio, Raffa Salvatore, Santino Iolanda
Abstract excerpt
The ability of some bacterial pathogens to activate Epithelial-Mesenchymal Transition normally is a consequence of the persistence of a local chronic inflammatory response or depends on a direct interaction of the pathogens with the host epithelial cells. In this study we monitored the abilities of the K. pneumoniae to activate the expression of genes related to EMT-like processes and the occurrence of phenotypic...
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