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TGF ‐β gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates

25 Jan 2016

Abstract excerpt

Genetic modification of marrow concentrates may provide convenient approaches to enhance the chondrogenic differentiation processes and improve the repair capacities in sites of cartilage defects following administration in the lesions. Here, we provided clinically adapted recombinant adeno-associated virus (rAAV) vectors to human bone marrow aspirates to promote the expression of the potent transforming growth...

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PMID: 26808466
DOI: 10.1111/jcmm.12774

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