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Article

Super-resolution microscopy as a potential approach to diagnosis of platelet granule disorders.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2016

Westmoreland D, Shaw M, Grimes W, Metcalf D J, Burden J J, Gomez K, Knight A E, Cutler D F

Abstract excerpt

BACKGROUND: Many platelet functions are dependent on bioactive molecules released from their granules. Deficiencies of these granules in number, shape or content are associated with bleeding. The small size of these granules is such that imaging them for diagnosis has traditionally required electron microscopy. However, recently developed super-resolution microscopes provide sufficient spatial resolution to...

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Source

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Identifiers

PMID: 26806224
DOI: 10.1111/jth.13269
PMCID: PMC4982064

Genes

HPS1
HPS5
HPS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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