Interactions between breast cancer susceptibility loci and menopausal hormone therapy in relationship to breast cancer in the Breast and Prostate Cancer Cohort Consortium.

doi:10.1007/s10549-016-3681-7

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Interactions between breast cancer susceptibility loci and menopausal hormone therapy in relationship to breast cancer in the Breast and Prostate Cancer Cohort Consortium.

Breast cancer research and treatment - 1 Feb 2016

Gaudet Mia M, Barrdahl Myrto, Lindström Sara, Travis Ruth C, Auer Paul L, Buring Julie E, Chanock Stephen J, Eliassen A Heather, Gapstur Susan M, Giles Graham G, Gunter Marc, Haiman Christopher, Hunter David J, Joshi Amit D, Kaaks Rudolf, Khaw Kay-Tee, Lee I-Min, Le Marchand Loic, Milne Roger L, Peeters Petra H M, Sund Malin, Tamimi Rulla, Trichopoulou Antonia, Weiderpass Elisabete, Yang Xiaohong R, Prentice Ross L, Feigelson Heather Spencer, Canzian Federico, Kraft Peter

Abstract excerpt

Current use of menopausal hormone therapy (MHT) has important implications for postmenopausal breast cancer risk, and observed associations might be modified by known breast cancer susceptibility loci. To provide the most comprehensive assessment of interactions of prospectively collected data on MHT and 17 confirmed susceptibility loci with invasive breast cancer risk, a nested case-control design among eight...

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Identifiers

PMID: 26802016
DOI: 10.1007/s10549-016-3681-7
PMCID: PMC5757510

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