Article
ELASPIC web-server: proteome-wide structure-based prediction of mutation effects on protein stability and binding affinity.
Bioinformatics (Oxford, England) - 15 May 2016
Witvliet Daniel K, Strokach Alexey, Giraldo-Forero Andrés Felipe, Teyra Joan, Colak Recep, Kim Philip M
Abstract excerpt
UNLABELLED: ELASPIC is a novel ensemble machine-learning approach that predicts the effects of mutations on protein folding and protein-protein interactions. Here, we present the ELASPIC webserver, which makes the ELASPIC pipeline available through a fast and intuitive interface. The webserver can be used to evaluate the effect of mutations on any protein in the Uniprot database, and allows all predicted results,...
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