Article
Breast cancer in BRCA mutation carriers: medical treatment.
Minerva ginecologica - 1 Oct 2016
Milani Andrea, Geuna Elena, Zucchini Giorgia, Aversa Caterina, Martinello Rossella, Montemurro Filippo
Abstract excerpt
About 10% of breast cancers are associated with the inheritance of autosomal dominant breast cancer susceptibility alleles BRCA1 and BRCA2. Until recently, the medical management of BRCA mutation-associated breast cancer has not differed from that of the sporadic breast cancer counterpart. However, there is mounting evidence that this molecular alteration confers sensitivity or resistance to systemic therapies...
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