Article
Abca7 deletion does not affect adult neurogenesis in the mouse.
Bioscience reports - 20 Jan 2016
Li Hongyun, Karl Tim, Garner Brett
Abstract excerpt
ATP-binding cassette transporter A7 (ABCA7) is highly expressed in the brain. Recent genome-wide association studies (GWAS) have identified ABCA7 single nucleotide polymorphisms (SNPs) that increase Alzheimer's disease (AD) risk, however, the mechanisms by which ABCA7 may control AD risk remain to be fully elucidated. Based on previous research suggesting that certain ABC transporters may play a role in the...
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